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The ongoing usage of benzodiazepines, which include VALIUM, may possibly lead to clinically considerable Bodily dependence. The hazards of dependence and withdrawal raise with for a longer time treatment method length and higher daily dose. Abrupt discontinuation or speedy dosage reduction of VALIUM right after ongoing use may possibly precipitate
Loss of life is a lot more normally connected to polysubstance use (Specially benzodiazepines with other CNS depressants for example opioids and Liquor).Mechanistically, employs molecular oxygen inserting just one oxygen atom into a substrate, and lessening the next into a water molecule, with two electrons provided by NADPH through cytochrome P450
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